Niacinamide (nahy-uh-sin-uh-mahyd) may seem confusing to say, but the skincare benefits of this vitamin B derivative are crystal clear. It’s no wonder this multitasking powerhouse is featured in everything from serums to moisturizers.

Here’s everything you need to know about niacinamide and why it deserves a spot in your skincare routine.

What is niacinamide?

Niacinamide is the biologically active form of vitamin B3, also known as niacin or nicotinic acid. It’s a water-soluble vitamin that’s naturally found in many foods and synthesized for use in skincare.

One of niacinamide’s standout features is its role as a potent antioxidant, which helps neutralize free radicals that damage skin cells. Its versatility and stability make it a hero ingredient for addressing a wide range of skin concerns, from hydration to acne control.

What are the benefits of niacinamide for skin?

Niacinamide is a powerful antioxidant and multitasking skincare ingredient that offers numerous benefits for all skin types.

#1 Strengthens the skin barrier

• Boosts ceramides production, locking in moisture and preventing water loss
• Protects against environmental damage by neutralizing free radicals

Try: SLMD Glycolic Acid Body Lotion

#2 Reduces redness and inflammation

• Calms irritated skin caused by acne, eczema, and rosacea
• Minimizes redness from environmental stressors like sun exposure

#3 Fights acne

• Reduces sebum production to help prevent clogged pores and breakouts
• Minimizes pore appearance for smoother, more refined skin texture
• Calms redness and inflammation associated with acne lesions

Try: SLMD BP Body Wash

#4 Combats signs of aging

• Fights oxidative stress to preserve skin’s elasticity
• Diminishes fine lines and wrinkles by stimulating collagen and elastin production
• Fades hyperpigmentation, including sunspots and post-inflammatory marks

Try: SLMD Vitamin C Serum, AHA/BHA Swipes

#5 Brightens and evens skin tone

• Reduces melanin production to fade discoloration and improve radiance
• Promotes a smoother, more uniform complexion

Who should use niacinamide?

Niacinamide is suitable for all skin types and ages, making it one of the most universally loved skincare ingredients.

• Sensitive skin: Calms irritation and strengthens the skin barrier
• Acne-prone skin: Regulates oil production and soothes inflammation
• Aging skin: Boosts elasticity and diminishes fine lines

Can you combine niacinamide with vitamin C?

There’s a common myth that niacinamide and vitamin C can’t be used together because they cancel each other out. This belief stems from outdated studies using unstable forms of these ingredients under extreme conditions.

Modern formulations have proven that niacinamide and vitamin C work well together, delivering complementary benefits like brightening and antioxidant protection.

Pro tip: Use a vitamin C serum in the morning and a niacinamide product at night, or look for a product that’s specially formulated to combine both ingredients effectively.

Try: SLMD Vitamin C Serum, AHA/BHA Swipes

How to use niacinamide in your skincare routine

Niacinamide is easy to incorporate into your daily skincare routine. Remember to follow product label instructions, and as always, talk to your dermatologist first if you're managing a clinical skin concern.

• When to use: Apply niacinamide morning or night, depending on your skincare goals.
• Application order: Use it after cleansing and before heavier creams or oils.
• Layering tip: Pair niacinamide with a hydrating ingredient like hyaluronic acid to maximize moisture retention and minimize irritation.

FAQ: Niacinamide in skincare

Q: Can niacinamide cause skin irritation?

A: While niacinamide is generally well-tolerated, some individuals may experience mild irritation, redness, or flushing, especially when using high concentrations or combining it with other active ingredients. If you've got sensitive skin, perform a patch test before full application and consult with a dermatologist if irritation occurs.

Q: Is niacinamide suitable for all skin types?

A: Yes, niacinamide is versatile and beneficial for all skin types, including sensitive, oily, acne-prone, and mature skin. Its anti-inflammatory and moisturizing properties make it a valuable addition to any skincare routine. Start by patch testing if you have concerns.

Q: How long does it take to see results from using niacinamide?

A: Improvements in skin texture and hydration can often be observed within 2–4 weeks of consistent use. For concerns like hyperpigmentation and fine lines, noticeable changes may take up to 8–12 weeks. Patience and regular application are key.

Q: Can I use niacinamide with other active ingredients like retinol or vitamin C?

A: Yes, niacinamide pairs well with many active ingredients, including retinol and vitamin C. To minimize the risk of irritation, you can stagger their application by using niacinamide in the morning and other actives like retinol at night. Niacinamide’s soothing properties may even help balance out potential irritation from stronger ingredients.ating potential irritation, making it a versatile component in combination therapies.

Q: Does niacinamide help with acne scars and hyperpigmentation?

A: Yes, niacinamide has been shown to reduce hyperpigmentation and improve skin tone by inhibiting melanin transfer. Regular use can lead to a more even-looking tone and diminished appearance of dark spots over time.